La Quinta Inn & Suites by Wyndham Sioux Falls

Experience Sioux Falls

Comfortable hotel off I-29 in the heart of the retail district

The perfect home away from home, La Quinta® by Wyndham Sioux Falls is located off I-29 and west 41st street. Our comfortable hotel is also just a short drive from the Great Plains Zoo & Delbridge Museum of Natural History, the W. H. Lyon Fairgrounds, and Sioux Falls Regional Airport (FSD). Explore the SculptureWalk that's spread throughout the downtown shopping district, learn something new at the Washington Pavilion, or hike the trails at the scenic Falls Park. Make the most of your stay with free daily breakfast, high-speed WiFi, and convenient shuttle service to and from the airport.

Refreshing Amenities

Settle in with free breakfast, WiFi, and our indoor pool

Enjoy a bright stay in Sioux Falls with our convenient amenities and signature Here for You service. Start your mornings with a free Bright Side Breakfast®, featuring waffles, scrambled eggs, biscuits and gravy, and more. We offer an indoor pool and a fitness center for daily exercise, in addition to free WiFi, an on-site business center, and a meeting facility. Unwind in one of our non-smoking guest rooms, with a mini-refrigerator, microwave, coffee maker, desk, ironing amenities, and a flat-screen HDTV. Plus, you'll appreciate extras like our manager's reception Monday through Thursday evenings and our complimentary airport shuttle.

Discover Sioux Falls

Explore landmarks, visit the zoo, and splash around a waterpark

Swim, splash, and slide at Wild Water West Waterpark, visit the Washington Pavilion of Arts and Sciences, or head to Sertoma Park, where you'll find the Butterfly House & Aquarium. Explore historic landmarks like the Queen Bee Mill Ruins or marvel at the triple waterfall at Falls Park. The Great Plains Zoo & Delbridge Museum of Natural History is a great place for family fun. Whether you want to shop at the Empire Mall or attend a concert, game, or special event at the Denny Sanford PREMIER Center, our hotel puts you close to it all.

Points of Interest

Butterfly House & Aquarium

Cathedral of Saint Joseph

Downtown Sioux Falls

Great Plains Zoo & Delbridge Museum of Natural History

Old Courthouse Museum

Pettigrew Home & Museum

Queen Bee Mill Ruins

Sioux Falls Convention Center

USS South Dakota Battleship Memorial

Washington Pavilion

W. H. Lyon Fairgrounds

Outdoors & Recreation

Big Sioux State Recreation Area

Falls Park

Great Bear Ski Valley

Japanese Gardens

SculptureWalk | Sioux Falls

Sertoma Park

Stockyards Ag Experience Plaza and Barn

Terrace Park

Thunder Road of Sioux Falls

Wild Water West Waterpark

Yankton Trail Park


Empire Mall

The Western Mall

Sports & Entertainment

Black Diamond Casino

Denny Sanford PREMIER Center

Sioux Falls Arena

Strawbale Winery

Thunder Road of Sioux Falls

Wilde Prairie Winery


Guest room at the La Quinta Inn & Suites by Wyndham Sioux Falls in Sioux Falls, South Dakota
La Quinta Inn & Suites by Wyndham Sioux Falls hotel lobby in Sioux Falls, South Dakota
Property amenity at La Quinta Inn & Suites by Wyndham Sioux Falls in Sioux Falls, South Dakota

Map & Directions

4521 W.41st St., Sioux Falls, SD, 57106



The Perfect Space for Meetings & Events

Plan your next special event or business meeting with us. Featuring 990 square feet of event space, our hotel offers a meeting room that accommodates up to 60 guests. We can also arrange great rates for groups of all sizes.