A Stress-Free Stay in Buffalo

Inviting hotel on the Buffalo Niagara Medical Campus, by BUF airport

Welcome to Wyndham Garden Buffalo Downtown, a convenient and comfortable hotel located on the Buffalo Niagara Medical Campus. You'll be steps from Buffalo General Medical Center, Gates Vascular Institute, Goslisano Children's Hospital of Buffalo, and Roswell Park Comprehensive Cancer Center. Explore the downtown area using our free local shuttle or schedule a shuttle ride to or from Buffalo Niagara International Airport (BUF) for an additional fee. Plus, our friendly front desk staff is available 24/7 for directions and local recommendations.

Redefining Expectations

Enjoy free WiFi, a gym, and area shuttle

Our fitness center makes it easy to keep up with your workout routine while the business center helps you stay productive. Keep your wardrobe fresh thanks to guest laundry facilities and enjoy a quick bite at the 24/7 hot meal station, offering variety of delicious, chef-prepared meals. Each non-smoking guest room features free WiFi, a flat-screen HDTV with cable, mini-refrigerator, microwave, coffee/tea maker, safe, hair dryer, and desk. You can also take advantage of our free downtown area shuttle and paid valet parking.

Explore Buffalo

Take it all in during your stay

There is so much to see and do in Buffalo, all just steps from our door. Visit historic sites and museums, catch a game, or learn about exotic wildlife at the zoo. There are also several local businesses in the area, making our hotel the perfect place for work or play.

Featured Rooms & Rates

Photos

Wyndham Garden Buffalo Downtown restaurant in Buffalo, New York

Bar at Wyndham Garden Buffalo Downtown in Buffalo, New York

Map & Directions

125 High Street, Buffalo, NY, 14203

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Amenities

Meetings, Events & Groups

The Perfect Space for Meetings & Events

Plan your next special event or business meeting with us. Featuring 1,745 square feet of event space, our hotel offers four meeting rooms that accommodate 202 conference guests or 50 banquet guests. We can also arrange great rates for groups of all sizes.

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