La Quinta Inn by Wyndham Amarillo Mid-City

All You Need in Amarillo

Contemporary hotel off I-40, near the airport and Route 66

Enjoy plentiful amenities and a convenient location at La Quinta Inn® by Wyndham Amarillo Mid-City. Located off I-40, our comfortable hotel is just five miles from the Rick Husband Amarillo International Airport (AMA) and offers easy access to top attractions like Cadillac Ranch and the Route 66 Historic District. Whatever brings you to this inviting city in the Texas Panhandle, you’ll appreciate our relaxing outdoor pool and fitness center. Stay connected with free WiFi and our on-site business center.

Amenities to Relax & Recharge

You'll love free breakfast and WiFi—plus, our pool and gym

Enjoy a bright stay in Amarillo with our convenient amenities and signature Here for You service. Start your mornings with a free Bright Side Breakfast® of hard boiled eggs, waffles, and more. We offer an outdoor pool so you can relax with a swim and a fitness center for daily workouts. Unwind in one of our pet-friendly guest rooms, featuring free high-speed WiFi, a flat-screen HDTV, mini-refrigerator, microwave, desk, coffee maker, ironing amenities, and hair dryer. Plus, take advantage of extras like free parking.

The Best of Amarillo

See cool art, visit Route 66, and hike a canyon

You'll find true Texas charm in Amarillo with cattle ranches, historic mansions, and scenic desert canyons. Be sure to visit the colorful Cadillac Ranch (a public art installation of graffiti-covered cars) and iconic Route 66 Historic District, a hub for dining, shopping, and nightlife. Family-friendly fun awaits at the impressive Palo Duro Canyon State Park, Amarillo Zoo, and Wonderland Amusement Park. Be sure to ask our friendly front desk staff for directions and local recommendations.

Points of Interest

Alibates Flint Quarries National Monument

Amarillo Botanical Gardens

American Quarter Horse Association

Downtown Amarillo

Helium Time Columns Monument

Jack Sisemore Traveland RV Museum

Lake Meredith National Recreation Area

Llano Cemetery

Palo Duro Canyon State Park

Polk Street

Santa Fe Building

Texas Panhandle War Memorial

Thompson Memorial Park

West Texas A&M University™

Wildcat Bluff Nature Center

Arts & Culture

Cadillac Ranch

Harrington House

Kwahadi Museum of the American Indian

Panhandle-Plains Historical Museum

Route 66 Historic District


6th Street Antique Mall

Beck Cowboy Boots

Cavender’s Boot City

Summit Shopping Center

West Texas Western Store

Westgate Mall

Wolflin Square

Sports & Entertainment

Amarillo Dragway

Amarillo Zoo

The Big Texan Steak Ranch

Buffalo Wild Wings®

Coyote Flight & Training Center

Don Harrington Discovery Center

Lights Off Golf

Old West Stables

Route 66 Motor Speedway

Wonderland Amusement Park


Guest room at the La Quinta Inn by Wyndham Amarillo Mid-City in Amarillo, Texas
La Quinta Inn by Wyndham Amarillo Mid-City suite in Amarillo, Texas
Guest room at the La Quinta Inn by Wyndham Amarillo Mid-City in Amarillo, Texas

Map & Directions

1708 I-40 East, Amarillo, TX, 79103-2114




Plan Your Group Travel with Us

Book your wedding party, sports team, or other group travel at our hotel. Submit a request for information about special rates on blocks of rooms.