La Quinta by Wyndham San Diego Mission Bay

Our property is currently undergoing renovations to the interior to better serve you. We thank you for your understanding.

Join Us in San Diego

Comfortable hotel off I-5 near Mission Bay Park and SeaWorld

Enjoy the California sunshine from the comfort and convenience of La Quinta® by Wyndham San Diego Mission Bay. While you're here, visit the world-famous San Diego Zoo, SeaWorld San Diego, Balboa Park, and Old Town San Diego State Historic Park. You'll also have easy access to San Diego International Airport (SAN). Make the most of your stay with free daily breakfast, high-speed WiFi, and our outdoor pool.

Refreshing Amenities

Enjoy our free breakfast, pool, and WiFi

A bright stay awaits at our San Diego hotel. With amenities like our outdoor pool with spa and our business center, you'll have everything you need for a productive trip. Get energized with our free Bright Side Breakfast® and stay connected to the office and friends with free WiFi. Each of our non-smoking guest rooms features a mini-refrigerator, microwave, desk, ironing amenities, and flat-screen HDTV. Plus, our hotel is pet-friendly and our staff is committed to delivering our signature Here for You service.

The Best of San Diego

Spend time with sea life, visit a museum, or enjoy the sunset

Our Mission Bay hotel puts you in position to explore everything San Diego has to offer. Discover Belmont Park, where you can ride the action-packed Big Dipper, a half-mile wooden track roller coaster known for its sharp curves and 70-foot drop. Dodge buckets of water and escape thundering waterfalls at Shipwreck Rapids or visit SeaWorld San Diego to see exciting aquatic shows. You can also see the pandas, giraffes, monkeys and more at San Diego Zoo, one of the most famous zoos in the country. Our knowledgeable staff is here to help you navigate it all during your stay.

Arts & Culture

Birch Aquarium at Scripps Institution of Oceanography

Maritime Museum of San Diego

Mormon Battalion Historic Site

Museum of Contemporary Art San Diego

San Diego Air & Space Museum

The San Diego Museum of Art

San Diego Museum of Man

San Diego Natural History Museum

USS Midway Museum

Whaley House Museum

Sports & Entertainment

Petco Park

SDCCU Stadium

Points of Interest

Balboa Park

Cabrillo National Monument

City Hall

Europa Village

Giant Dipper

Liberty Station

LEGOLAND California

Little Italy

Mt. Soledad National Veterans Memorial

Old Town San Diego State Historic Park

Santa Rosa Plateau Ecological Reserve

Outdoors & Recreation

Aquatica Waterpark

Belmont Park

Dog Beach

Gaslamp Quarter

Journey to Atlantis

La Jolla Cove

Mission Bay Park

SeaWorld San Diego

San Diego Zoo

Sam Hicks Monument Park

Seaport Village

Sequoia National Park

Sunset Cliffs

Tecolote Canyon Natural Park and Nature Center


Guest room at the La Quinta by Wyndham San Diego Mission Bay in San Diego, California
La Quinta by Wyndham San Diego Mission Bay hotel lobby in San Diego, California
Guest room at the La Quinta by Wyndham San Diego Mission Bay in San Diego, California

Map & Directions

4610 De Soto St., San Diego, CA, 92109



Plan Your Group Travel with Us

Book your wedding party, sports team, or other group travel at our hotel. Submit a request for information about special rates on blocks of rooms.