AmericInn by Wyndham Chamberlain Conference Center

    A Pleasant Stay in Chamberlain

    Inviting, pet-friendly hotel off I-90 near the Missouri River

    Located off I-90, our AmericInn Lodge & Suites Chamberlain - Conference Center hotel offers easy access to the Missouri River, Red Lake, and Fort Pierre National Grassland. Experience genuine hospitality with our friendly front desk staff and amenities like free WiFi, an indoor pool, and 24/7 fitness center. Whether you’re here for business or pleasure, you’ll enjoy our proximity to South Dakota’s top attractions as well as the capital city of Pierre, which is within driving distance.

    Sensible Comforts

    Make the most of your stay with free breakfast and WiFi—plus, our indoor pool

    Start your day with a dip in our indoor pool or a workout in our 24/7 fitness center, and then fuel up with a homestyle breakfast served every morning. From free WiFi to comfortable beds, our well-equipped guest rooms are outfitted with everything you need for a stress-free visit. All accommodations feature a flat-screen HDTV, mini-refrigerator, microwave, and coffee maker. For extra space and amenities, upgrade to a suite with a whirlpool tub or fireplace—or, book a pet-friendly room for an additional fee.

    Welcome to Chamberlain

    Go fishing, hunting, or museum hopping

    Situated along the Missouri River, our Chamberlain hotel puts you within reach of some of South Dakota’s most scenic spots. Fishing is one of the area’s main draws with opportunities on the Missouri River, Red Lake, and Fort Pierre National Grassland. Chamberlain is also home to the Lewis and Clark Interpretive Center, which features a re-creation of the expedition's 55-foot keelboat, and the Akta Lakota Museum & Cultural Center. There is also great pheasant, grouse, deer, and waterfowl hunting in the area. Plus, you can easily take a day trip to Pierre to see the capital city’s top attractions.


    Guest room at the AmericInn by Wyndham Chamberlain Conference Center in Chamberlain, South Dakota

    Map & Directions

    1981 East King Street, Chamberlain, SD, 57325




    Backwoods Lounge

    At the end of a long day, unwind with a beer or glass of wine at our laid-back bar. Open Tues–Sat at 5:00 p.m.


    The Perfect Space for Meetings & Events

    Plan your next special event or business meeting with us. Featuring over 4,000 square feet of event space, our hotel’s 4 meeting rooms accommodate up to 300 conference or banquet guests. We can also arrange great rates for groups of all sizes.