Knights Inn Santee


Southern Hospitality in Santee

Off I-95 near Lake Marion, Santee State Park, and area golf courses

Our Knights Inn Santee hotel is conveniently located right off I-95, just down the road from the sprawling Santee State Park and Lake Marion—South Carolina’s largest lake. Our pet-friendly hotel puts you within minutes of restaurants and popular attractions along the Santee River Valley. Play a round of 18 at one of 3 golf courses in town: Santee National Golf Club, Santee Cooper Country Golf Club, and Lake Marion Golf Course. We’re also set directly between Charleston and Columbia, so you can visit either city with ease.

Clear, Uncomplicated Value

Enjoy our free breakfast, free WiFi, and our seasonal pool

Start your morning with our free continental breakfast, and stay connected with free WiFi. Dive into our seasonal outdoor pool to refresh. Each guest room features a flat-screen HDTV with cable, sitting area, mini-refrigerator, microwave, hairdryer, and coffee maker. Pet-friendly roomas are available for a nominal fee, and we offer free parking for car, truck, or RV.

Take It All In

Fish in Lake Marion, hit the links, or day trip to a city

Pack your clubs and tee off at one of several nearby golf courses including Santee Cooper Golf Club and Lake Marion Golf Course. Go fishing, boating, and kayaking on South Carolina's largest lake, Lake Marion. For incredible wilderness and wildlife hikes, visit Santee National Wildlife Refuge. If you are staying with us in August, check out the Big Daddy Fishing Event at Santee State Park. We’re also completely surrounded by restaurants, so it’s easy to dine before heading to the lake. Take the interstate to Charleston or Columbia, both just over an hour away.

Knights Inn Santee hotel lobby in Santee, South Carolina
Guest room at the Knights Inn Santee in Santee, South Carolina
Guest room at the Knights Inn Santee in Santee, South Carolina
Map & Directions

249 Britain Street, Santee, SC, 29142

Group Bookings

Plan Your Group Travel With Us

Book your wedding party, sports team, or other group travel at our hotel. Submit your request for information about special rates on blocks of rooms.