La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

    Stay Refreshed in Rochester

    Convenient hotel off US-63 near the Mayo Clinic and ROC airport

    Welcome to La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S, located in southeastern Minnesota just off US-63, four miles from Rochester International Airport (ROC). Situated five miles from downtown Rochester and close to the Mayo Clinic, we're an ideal choice for both business and leisure travelers alike. If you're in town for work, you can make use of our business center, two meeting rooms, and free WiFi while enjoying easy access to local businesses like IBM and Seneca Foods. An indoor saltwater pool and pet-friendly rooms round out a great stay in Rochester.

    Bright Amenities

    You'll love free breakfast and WiFi—plus, our saltwater pool

    Enjoy a bright stay in Rochester with our convenient amenities and signature Here for You service. Start your mornings with a free Bright Side Breakfast® of eggs, waffles, fruit, and more. We offer an indoor saltwater pool so you can relax with a swim and a fitness center for daily workouts, in addition to free WiFi and an on-site business center. Unwind in one of our non-smoking guest rooms, featuring a mini-refrigerator, microwave, and coffee maker. Plus, you'll appreciate extras like electric vehicle charging stations.

    Make the Most of Rochester

    Visit museums, spend time lakeside, or go shopping

    Nestled in southern Minnesota, Rochester offers plenty of museums and parks to explore. Visit the Minnesota Children's Museum for interactive exhibits, learn about the area's rich past at the History Center of Olmsted County, or see local artwork at the Rochester Art Center. The downtown area is full of restaurants and stores, while many nearby golf courses offer plenty of opportunities to hit the links. If you're looking to relax, enjoy a lakeside picnic with views of Rochester's skyline.

    Arts & Culture

    Charles E. Gagnon Museum & Sculpture Garden

    History Center of Olmsted County

    Mayo Civic Center

    Minnesota Children's Museum

    Museum of Automotive History

    Rochester Art Center

    Points of Interest

    Mayo Clinic

    Mayowood Mansion

    Plummer House

    Zumbro River

    Outdoors & Recreation

    Bear Creek Park

    Cascade Lake Park

    Interlachen Lake

    Manorwoods Lake

    Mohn Park

    Northern Heights Park

    Parkwood Hills Park

    Plummer House Park

    Quarry Hill Park and Nature Center

    Silver Lake Park

    Slatterly Park

    Soldiers Field Veterans Memorial


    Apache Mall

    Crossroads Center

    Maplewood Square

    River Center

    Shops at University Square

    Silver Lake Shopping Center

    Sports & Entertainment

    Eastwood Golf Course

    Fuad Mansour Sports Complex

    Oak Summit Golf Course

    Soldiers Field Golf Course


    Pool at the La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S in Rochester, Minnesota
    Guest room at the La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S in Rochester, Minnesota

    Map & Directions

    4353 Canal Place SE, Rochester, MN, 55904




    The Perfect Space for Meetings & Events

    Plan your next special event or business meeting with us. Featuring 1,400 square feet of event space, our hotel offers two meeting rooms that accommodate up to 60 guests. We can also arrange great rates for groups of all sizes.