La Quinta Inn & Suites by Wyndham Manhattan Midtown

Stay in the Heart of New York City

Contemporary hotel near Times Square and the Theater District

Enjoy thoughtful amenities and an ultra-convenient location at La Quinta by Wyndham Manhattan Midtown. Our pet-friendly hotel offers easy access to the subway, as well as three major airports: LaGuardia (LGA), John F. Kennedy International (JFK), and Newark Liberty International (EWR). You’ll be surrounded by fantastic dining and shopping and within walking distance of attractions like Times Square, the Theater District, and the Empire State Building. If work brings you here, we’re only .5 mile from the Jacob K. Javits Convention Center.

Staying with us on November 20? You can de-stress on the busiest business travel day of the year thanks to our “Take a Paws” Project, featuring anxiety-reducing weighted blankets, fitness and meditation classes, pet therapy sessions in the lobby, and more.

Bright Amenities

You’ll love free breakfast and WiFi, plus our fitness center

Our everyday essentials and signature Here for You service shine bright. Wake up with a free Bright Side Breakfast® of eggs, pastries, oatmeal, and more to get energized for your day. We offer a fitness center for daily workouts, in addition to free WiFi and an on-site business center. Unwind in one of our non-smoking guest rooms, featuring a flat-screen HDTV, desk, safe, ironing amenities, hair dryer, and bottled water.  Plus, you’ll appreciate extras like our pet-friendly rooms and same-day dry cleaning.

Discover NYC

See masterpieces at the Met, go shopping, or head to Little Italy

Visit world-class art museums like the Met and MoMA, see iconic landmarks such as Rockefeller Center® and the Statue of Liberty, and stroll through Central Park or the railway-line-turned-park known as the High Line. Shoppers will delight in the nearby location of Macy’s Herald Square and Hudson Yards™, while sports fans can catch a pro game in every season. You can also wander unique neighborhoods like Chinatown and Little Italy, see a Broadway show, and check out culinary hotspots like Chelsea Market.

Arts & Culture

American Museum of Natural History

Apollo Theater

Brooklyn Museum

Carnegie Hall

The Frick Collection

Intrepid Sea, Air & Space Museum

Jewish Museum

Lincoln Center

Madame Tussauds New York

The Met Cloisters

The Metropolitan Museum of Art (The Met)

Museum of Jewish Heritage

The Museum of Modern Art (MoMA)

National September 11 Memorial & Museum

New-York Historical Society Museum & Library

Radio City Music Hall

Solomon R. Guggenheim Museum

Tenement Museum

Theater District

Whitney Museum of American Art

Points of Interest

Brooklyn Bridge


Chrysler Building 

Ellis Island 

Empire State Building

Grand Central Terminal

Greenwich Village

Jacob K. Javits Convention Center

Little Italy

New York Public Library

One World Trade Center / One World Observatory

Penn Station

Rockefeller Center

South Street Seaport

St. Patrick’s Cathedral

Statue of Liberty

Times Square

United Nations Headquarters

Outdoors & Recreation

Bryant Park

Bronx Zoo

Brooklyn Bridge Park

Central Park

High Line

Hudson River Park

New York Botanical Garden


Brookfield Place

Chelsea Market

Fifth Avenue

Hudson Yards

Macy’s Herald Square


The Shops at Columbus Circle

Westfield World Trade Center

Sports & Entertainment

Barclays Center Brooklyn / Brooklyn Nets & New York Islanders

Citi Field / New York Mets

Coney Island

Macy’s Thanksgiving Day Parade

Madison Square Garden / New York Knicks & New York Rangers

MetLife Stadium / New York Giants & New York Jets

Prudential Center / New Jersey Devils

Yankee Stadium / New York Yankees


La Quinta Inn & Suites by Wyndham Manhattan Midtown hotel lobby in New York, New York
Guest room at the La Quinta Inn & Suites by Wyndham Manhattan Midtown in New York, New York

Map & Directions

333 West 38th Street, New York, NY, 10018



Plan Your Group Travel with Us

Book your wedding party, sports team, or other group travel at our hotel. Submit a request for information about special rates on blocks of rooms.